别构连接与相变

Physiol Chem Phys. 1976;8(2):143-50.

The thermodynamics of allosteric linkage are observed to be analogous to those of a phase transition. When a phenomenological theory of phase transitions is applied to the allosteric interactions in hemoglobin, a generalized Hill equation is arrived at, including an explicit dependence on temperature. This result is in good agreement with experiments.

变构连接的热力学被观察到类似于相变的热力学。当将相变的唯象理论应用于血红蛋白中的变构相互作用时，得到了一个广义的希尔方程，其中明确包含了对温度的依赖。这一结果与实验结果高度吻合。