Nomura M, Nada T, Endo J, Kondo Y, Yukinaka M, Saito K, Ito S, Mori H, Nakaya Y, Shinomiya H
Second Department of Internal Medicine, School of Medicine, University of Tokushima, Japan.
Heart. 1998 Aug;80(2):194-6. doi: 10.1136/hrt.80.2.194.
A 44 year old man with Brugada syndrome and ventricular fibrillation had an autonomic disorder, shown by spectral analysis of heart rate variability and 123I-MIBG myocardial scintigraphy. Periodic variation of the ST segments was detected by Holter ECG. Increased high frequency power (0.15-0.40 Hz), an index of parasympathetic nerve activity, was observed just before ST segment elevation. In addition, local dysfunction of sympathetic nerves in the left ventricle was detected by 123I-MIBG myocardial scintigraphy. Unbalanced autonomic nerve function plays an important role in inducing Brugada-type ECG signs.
一名患有Brugada综合征和心室颤动的44岁男性存在自主神经功能紊乱，这通过心率变异性频谱分析和123I-MIBG心肌闪烁显像得以证实。动态心电图检测到ST段的周期性变化。在ST段抬高前观察到高频功率（0.15 - 0.40赫兹）增加，这是副交感神经活动的一个指标。此外，123I-MIBG心肌闪烁显像检测到左心室交感神经局部功能障碍。自主神经功能失衡在诱发Brugada型心电图表现中起重要作用。
