Nahas Z, Arlinghaus K A, Kotrla K J, Clearman R R, George M S
Medical University of South Carolina, Department of Psychiatry, Charleston, SC 29403, USA.
J Neuropsychiatry Clin Neurosci. 1998 Fall;10(4):453-5. doi: 10.1176/jnp.10.4.453.
Emotional incontinence (EI) is a perturbing condition characterized by uncontrollable outbursts of exaggerated, involuntary facial expressions and pathological crying or laughter. There is increasing evidence that serotonergic neurotransmission may be damaged in EI. The authors report 4 pathological crying cases (3 poststroke and 1 with multiple sclerosis) and 1 case of pathological laughter after traumatic brain injury. EI improved dramatically with three different selective serotonin reuptake inhibitors (fluoxetine, sertraline, and paroxetine) in the context of these different CNS diseases.
情感失禁（EI）是一种令人困扰的病症，其特征为无法控制地爆发夸张、不自主的面部表情以及病理性哭笑。越来越多的证据表明，EI 中血清素能神经传递可能受损。作者报告了 4 例病理性哭泣病例（3 例中风后病例和 1 例多发性硬化症病例）以及 1 例创伤性脑损伤后的病理性大笑病例。在这些不同的中枢神经系统疾病背景下，三种不同的选择性 5-羟色胺再摄取抑制剂（氟西汀、舍曲林和帕罗西汀）使 EI 显著改善。
