Carpentier P H
Service de médecine interne gérontologie clinique et angiologie, Centre hospitalier universitaires de Grenoble.
Rev Prat. 1998 Oct 1;48(15):1641-6.
Vascular acrosyndromes group several disorders around Raynaud's phenomenon, characterized by a distal involvement and a vasomotor pathogenesis. Their exact mechanisms remain unknown, but epidemiological data favour disturbances of thermoregulation: cold climate, outdoor occupation and low body mass index are significant risk factors for most of them. Acrosyndromes with vasoconstriction are highly prevalent in France: 10 to 15% for Raynaud's phenomenon and acrocyanosis; 2 to 6% for chilblains. Acrosyndromes with vasodilatation (acrocholose, erythermalgia) are much rare. There is no link between Raynaud's phenomenon and tobacco use, alcohol consumption, oestrogen treatment, carpal tunnel syndrome or thoracic outlet syndrome. By contrast, the role of connective tissue diseases and occupational disorders (vibration exposure and hand-hammer syndrome) are established.
血管性肢端综合征包含围绕雷诺现象的几种病症，其特征为远端受累和血管舒缩发病机制。其确切机制尚不清楚，但流行病学数据支持体温调节紊乱：寒冷气候、户外工作和低体重指数是其中大多数病症的重要危险因素。血管收缩性肢端综合征在法国极为常见：雷诺现象和手足发绀症的患病率为10%至15%；冻疮的患病率为2%至6%。血管扩张性肢端综合征（肢端发绀、红斑性肢痛症）则较为罕见。雷诺现象与吸烟、饮酒、雌激素治疗、腕管综合征或胸廓出口综合征之间没有关联。相比之下，结缔组织病和职业性疾病（振动暴露和手锤综合征）的作用已得到证实。
