Naaeder S B, Evans D F, Archampong E Q
Department of Surgery, University of Ghana Medical School, Accra, Ghana.
West Afr J Med. 1998 Jul-Sep;17(3):165-7.
Dietary fibre supplementations studies to evaluate the effect of dietary fibre on colonic and faecal pH have relied on the use of the unabsorbed disaccharide and osmotic laxative lactulose. We studied the effect of chronic dietary fibre supplementation on colonic pH in healthy British volunteers who consumed a normal mixed diet but who consumed a normal mixed diet but who were asked to double their daily intake of dietary fibre from their usual fibre sources. The median dietary fibre intake of the 5 male volunteers was 17.5 g/day. This was doubled to 34.4 g/day. The pH in all the parts of the colon decreased progressively during the period of study, being lowest at the end of two weeks of fibre supplementation. The pH returned to the presupplementation values within two weeks of cessation of fibre supplementation. This study has shown that the effect of dietary fibre on colonic pH is short-lived and therefore its use for dietary intervention in large bowel diseases should be indefinite.
评估膳食纤维对结肠和粪便pH值影响的膳食纤维补充研究一直依赖于使用未被吸收的二糖和渗透性泻药乳果糖。我们研究了长期补充膳食纤维对健康英国志愿者结肠pH值的影响，这些志愿者食用正常混合饮食，但被要求将日常膳食纤维摄入量从通常的纤维来源翻倍。5名男性志愿者的膳食纤维摄入量中位数为17.5克/天，翻倍至34.4克/天。在研究期间，结肠所有部位的pH值逐渐下降，在补充纤维两周结束时最低。在停止补充纤维两周内，pH值恢复到补充前的值。这项研究表明，膳食纤维对结肠pH值的影响是短暂的，因此其用于大肠疾病的饮食干预应该是不确定的。
