Fromanek A, Korbuly D, Moore R, Knight L, Kim S, Amplatz K
Radiology. 1976 Dec;121(3 Pt. 1):541-4. doi: 10.1148/121.3.541.
The effect of Valium on coronary blood flow was studied. In 18 patients undergoing coronary angiography, total and regional myocardial blood flow was determined by the 133Xe wash-out technique. A total of 39 pre- and 39 post-Valium injection wash-out curves were constructed. Results indicate (99% confidence) that intravenous Valium injection (0.1 mg/kg body weight) decreases myocardial blood flow 12--15%.
研究了安定对冠状动脉血流量的影响。对18例接受冠状动脉造影的患者，采用133Xe洗脱技术测定了全心和局部心肌血流量。共构建了39条注射安定前和39条注射安定后的洗脱曲线。结果表明（99%置信度），静脉注射安定（0.1mg/kg体重）可使心肌血流量减少12% - 15%。
