Mirz F, Jørgensen B G, Pedersen C B
Arhus Universitetshospital, Arhus Kommunehospital, øre-naese-halsafdeling H.
Ugeskr Laeger. 1998 Nov 2;160(45):6516-9.
During the period 1977-1996 142 vestibular schwannomas in 138 patients in a well-defined population in the County of Aarhus, Denmark were registered. The incidence of vestibular schwannomas changed from approximately six tumours pr. million inhabitants in the years 1977-1981 to 18 tumours pr. million in the period 1992-1996. Most tumours were operated, a smaller group of vestibular schwannomas were observed by repetitive tomographic imaging, due to small tumour size, advanced age, poor health conditions or the patient's refusal of operation. Whether the strategy for the treatment of vestibular schwannomas is an immediate operation or observation of selected patients, the future management of the increasing number of vestibular schwannomas will require an extension of the present surgical and MR-imaging capacity.
在1977年至1996年期间,丹麦奥胡斯郡一个明确界定人群中的138名患者身上的142例前庭神经鞘瘤被登记在册。前庭神经鞘瘤的发病率从1977年至1981年期间每百万居民约6例肿瘤,变为1992年至1996年期间每百万18例肿瘤。大多数肿瘤接受了手术治疗,一小部分前庭神经鞘瘤由于肿瘤体积小、年龄大、健康状况差或患者拒绝手术,通过重复断层成像进行观察。无论前庭神经鞘瘤的治疗策略是立即手术还是对选定患者进行观察,未来对越来越多的前庭神经鞘瘤的管理都将需要扩大目前的手术和磁共振成像能力。