Stangerup Sven-Eric, Caye-Thomasen Per, Tos Mirko, Thomsen Jens Christian
Slettebjerget 83, DK-3400 Hillerød.
Ugeskr Laeger. 2008 Oct 13;170(42):3335-8.
During the last 30 years the number of diagnosed vestibular schwannomas (VS) has increased from 15 in 1976 to 116 in 2006. The aim of this study is to describe and analyse this increase.
In Denmark, the handling of VS patients has been centralised since 1976. Since 1976, 2046 new cases of unilateral VS have been diagnosed.
In 1976, 15 VS were diagnosed. Since then, the number of diagnosed tumours has increased almost linearly to 116 in 2006. The size of the diagnosed tumours has decreased from 35 mm in 1979 to 10 mm in 2006. In the beginning of the period, giant tumours dominated in contrast to the end of the period where the small tumours dominated. The mean age at the time of diagnosis has been slowly increasing from 50 years in the beginning to almost 60 years at the end of the period.
With easier access to MRI, vestibular schwannomas are found earlier when they are still small. The increase in the number of diagnosed tumours is mainly explained by the diagnosis of intrameatal and small tumours in the older age group which was not previously offered MRI examination.
在过去30年中,已诊断出的前庭神经鞘瘤(VS)数量从1976年的15例增加到2006年的116例。本研究的目的是描述和分析这种增长情况。
自1976年以来,丹麦对VS患者的治疗已实现集中化。自1976年以来,已诊断出2046例单侧VS新病例。
1976年诊断出15例VS。从那时起,诊断出的肿瘤数量几乎呈线性增加,到2006年达到116例。已诊断肿瘤的大小从1979年的35毫米降至2006年的10毫米。在这一时期开始时,巨大肿瘤占主导,而在这一时期结束时,小肿瘤占主导。诊断时的平均年龄已从开始时的50岁缓慢增加到这一时期结束时的近60岁。
随着MRI检查的更容易获得,前庭神经鞘瘤在仍较小的时候就被更早发现。诊断出的肿瘤数量增加主要是由于老年组内耳道内和小肿瘤的诊断,而这些患者以前未接受MRI检查。