Metz L
Department of Clinical Neurosciences, Faculty of Medicine, University of Calgary and University of Calgary MS Clinic, Foothills Hospital, Alberta, Canada.
Semin Neurol. 1998;18(3):389-95. doi: 10.1055/s-2008-1040888.
Although new disease-altering treatments offer hope for those with multiple sclerosis, they are not appropriate for most. Management of symptoms, however, can help everyone with the disease. Several new therapies, including tizanidine, intrathecal baclofen, botulinum toxin injections, gabapentin, ondansitron, thalamic stimulation, and lamotrigine, increase our treatment options. Better understanding of the sleep disorders that commonly occur in those with multiple sclerosis will help us treat another disabling symptom. This chapter reviews the medical and surgical management of multiple sclerosis symptoms, including these new options.
尽管新的疾病改变疗法为多发性硬化症患者带来了希望，但它们并不适用于大多数患者。然而，症状管理对每个患有该疾病的人都有帮助。几种新的疗法，包括替扎尼定、鞘内注射巴氯芬、肉毒杆菌毒素注射、加巴喷丁、昂丹司琼、丘脑刺激和拉莫三嗪，增加了我们的治疗选择。更好地了解多发性硬化症患者中常见的睡眠障碍将有助于我们治疗另一种致残症状。本章回顾了多发性硬化症症状的药物和手术管理，包括这些新的选择。
