Lindahl D, Palmer J, Pettersson J, White T, Lundin A, Edenbrandt L
Department of Clinical Physiology, Lund University, Sweden.
Clin Physiol. 1998 Nov;18(6):554-61. doi: 10.1046/j.1365-2281.1998.00134.x.
The bull's-eye image, also called polar map image, has been developed as an important display for the visual and quantitative analysis of myocardial perfusion scintigrams. Quantitative analysis can be performed for example by comparing areas in the bull's-eye image with normal limits or by processing it using artificial neural networks. The usefulness of such methods is highly dependent on the information content of the bull's-eye image. The purpose of this study was to investigate whether there is more diagnostically important information in a set consisting of the myocardial bull's-eye image plus tomographic slice image than in the bull's-eye image alone. A population of 135 patients who had undergone both myocardial scintigraphy and coronary angiography, with no more than 3 months elapsing between the two examinations, was studied retrospectively. Four experienced observers independently classified visually all scintigrams regarding the presence/absence of coronary artery disease in two vascular territories using a four-grade scale. The observers classified the scintigrams once viewing bull's-eye images only, and once viewing tomographic slices and bull's-eye images. Coronary angiography was used as gold standard. The classifications were evaluated using the areas under the receiver operating characteristics (ROC) curves. The classifications based on bull's-eye images only were slightly more accurate than those based on tomographic slices and bull's-eye images in one of the two vascular territories (ROC areas of 0.66 vs. 0.64). The opposite relationship was found in the other vascular territory (0.78 vs. 0.81). None of the differences was statistically significant. In conclusion, the diagnostically important information for the diagnosis of coronary artery disease by myocardial perfusion scintigraphy is present in the bull's-eye image.
靶心图，也称为极坐标图，已被开发成为心肌灌注闪烁图视觉和定量分析的一种重要显示方式。例如，可以通过将靶心图中的区域与正常范围进行比较，或者使用人工神经网络对其进行处理来进行定量分析。这些方法的有效性高度依赖于靶心图的信息含量。本研究的目的是调查由心肌靶心图加断层切片图像组成的一组图像中是否比单独的靶心图包含更多具有诊断重要性的信息。对135例接受过心肌闪烁扫描和冠状动脉造影的患者进行了回顾性研究，两次检查之间的时间间隔不超过3个月。四名经验丰富的观察者使用四级量表，独立地对所有闪烁图在两个血管区域内是否存在冠状动脉疾病进行视觉分类。观察者分别仅查看靶心图一次，以及查看断层切片和靶心图一次。冠状动脉造影用作金标准。使用受试者操作特征（ROC）曲线下的面积对分类进行评估。在两个血管区域之一中，仅基于靶心图的分类比基于断层切片和靶心图的分类略准确一些（ROC面积分别为0.66对0.64）。在另一个血管区域中发现了相反的关系（0.78对0.81）。这些差异均无统计学意义。总之，心肌灌注闪烁扫描诊断冠状动脉疾病的具有诊断重要性的信息存在于靶心图中。
