Hansma H G, Pietrasanta L
Department of Physics, University of California, Santa Barbara 93106, USA.
Curr Opin Chem Biol. 1998 Oct;2(5):579-84. doi: 10.1016/s1367-5931(98)80086-0.
The highlight of the past year is the unfolding and refolding of the muscle protein titin in the atomic force microscope. A related highlight in the intersection between experiment and theory is a recent review of the effects of molecular forces on biochemical kinetics. Other advances in scanning probe microscopy include entropic brushes, molecular sandwiches and applications of atomic force microscopy to gene therapy.
