Pellat J, Perret J, Pasquier B, Crouzet G, Dubos G, Chateau R
Rev Neurol (Paris). 1976 Aug;132(8):517-35.
The authors describe the case of a patient of 22 with hypertension and livedo reticularis who, after presenting with a left brachial monoparesis became progressively demented over a period of five years and died at the age of 27 from a cerebro-meningeal haemorrhage. Angiographically, diffuse distal obliteration of the cerebral arteries was seen with deep networks of the moyamoya type involving the lenticulostriate arteries; similar changes were present in the upper left limb. Histopathological investigations showed obliterative thromboangiitis affecting not only the cerebrum, the brain stem and the cerebellum, but also the viscera. Analysis of this case and consideration of the theoretical possibilities leads the authors to urge that thromboangiosis together with its cerebral manifestations should be considered a nosological entity.
作者描述了一名22岁患有高血压和网状青斑的患者病例，该患者在出现左上肢单瘫后，在五年内逐渐痴呆，27岁时死于脑-脑膜出血。血管造影显示，大脑动脉弥漫性远端闭塞，伴有豆纹动脉受累的烟雾病样深部血管网；左上肢上部也有类似变化。组织病理学检查显示，闭塞性血栓性血管炎不仅影响大脑、脑干和小脑，还累及内脏。对该病例的分析以及对理论可能性的考虑，促使作者敦促将血栓性血管病及其脑部表现视为一种病种实体。
