Cui X, Sakaguchi T, Ishizuka D, Tsukada K, Hatakeyama K
The First Department of Surgery, Niigata University School of Medicine, Japan.
J Int Med Res. 1998 Aug-Sep;26(4):181-7. doi: 10.1177/030006059802600402.
The effects of ginseng extract (from the root of Panax ginseng) on factors inducing fatty liver were examined in 66% hepatectomized rats. Oral administration of ginseng extract at 125 or 250 mg/kg/day produced statistically significant reductions in total cholesterol and triglyceride concentrations in the blood 3 days after hepatectomy (P<0.05); the total cholesterol response appeared to be dose-related. Administration of ginseng extract at both doses also reduced total cholesterol and triglyceride concentrations in the liver 3 days after hepatectomy. Food intake and serum chemistry parameters indicating liver and kidney function were unchanged after ginseng administration except for the lipid metabolic parameters. These observations suggest that orally administered ginseng extract can suppress the formation of fatty liver after hepatic resection.
在66%肝切除大鼠中研究了人参提取物（来源于人参根）对诱导脂肪肝因素的影响。肝切除术后3天，以125或250mg/kg/天的剂量口服人参提取物，可使血液中总胆固醇和甘油三酯浓度显著降低（P<0.05）；总胆固醇反应似乎与剂量相关。两种剂量的人参提取物给药在肝切除术后3天也降低了肝脏中总胆固醇和甘油三酯浓度。除脂质代谢参数外，人参给药后食物摄入量以及表明肝肾功能的血清化学参数均未改变。这些观察结果表明，口服人参提取物可抑制肝切除术后脂肪肝的形成。
