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青少年和青年社区样本中广场恐惧症与惊恐障碍的关系。

The relationship of agoraphobia and panic in a community sample of adolescents and young adults.

作者信息

Wittchen H U, Reed V, Kessler R C

机构信息

Department of Clinical Psychology, Max Planck Institute of Psychiatry, Munich, Germany.

出版信息

Arch Gen Psychiatry. 1998 Nov;55(11):1017-24. doi: 10.1001/archpsyc.55.11.1017.

Abstract

BACKGROUND

Data are presented on the prevalence of DSM-IV panic and agoraphobia in a community sample of adolescents and young adults in Munich, Germany.

METHODS

A total of 3021 respondents aged 14 to 24 years were assessed with a revised version of the Composite International Diagnostic Interview (CIDI). Respondents classified as having agoraphobia without panic were subtyped by number of agoraphobic trigger situations and subjected to a clinical review.

RESULTS

Lifetime prevalence of DSM-IV agoraphobia in the revised CIDI was higher (8.5%) than that of panic attack (4.3%) or panic disorder with (0.8%) or without (0.8%) agoraphobia. Marked differences in symptomatology, course, and associated impairments between panic disorder and agoraphobia were found. Most patients with agoraphobia reported neither full nor limited attacks or uncued paniclike experiences. Clinical review revealed that many respondents classified by the CIDI as having agoraphobia actually have specific phobia, resulting in a corrected agoraphobia prevalence of 3.5%. Number of agoraphobia trigger situations was identified as a useful way of differentiating patients with true agoraphobia from those with simple phobia. Even after correcting for overdiagnosis, however, the majority of respondents with confirmed agoraphobia were found not to have a prior history of panic.

CONCLUSIONS

The results call into question the assumed key pathogenic role of panic attacks in the onset of agoraphobia. Consistent with findings that agoraphobia without panic is rarely seen in clinical settings, we find that such patients seldom seek professional treatment.

摘要

背景

本文呈现了德国慕尼黑一个青少年和青年社区样本中 DSM-IV 惊恐障碍和广场恐惧症的患病率数据。

方法

采用修订版的复合国际诊断访谈(CIDI)对总共 3021 名年龄在 14 至 24 岁的受访者进行评估。被归类为患有无惊恐发作的广场恐惧症的受访者,根据广场恐惧症触发情境的数量进行亚型分类,并接受临床审查。

结果

修订版 CIDI 中 DSM-IV 广场恐惧症的终生患病率(8.5%)高于惊恐发作(4.3%)、伴有广场恐惧症的惊恐障碍(0.8%)或不伴有广场恐惧症的惊恐障碍(0.8%)。惊恐障碍和广场恐惧症在症状学、病程及相关损害方面存在显著差异。大多数广场恐惧症患者既未报告完全发作也未报告有限发作或无提示的惊恐样体验。临床审查显示,许多被 CIDI 归类为患有广场恐惧症的受访者实际上患有特定恐惧症,导致校正后的广场恐惧症患病率为 3.5%。广场恐惧症触发情境的数量被确定为区分真正的广场恐惧症患者和单纯恐惧症患者的一种有用方法。然而,即使校正了过度诊断,大多数确诊为广场恐惧症的受访者也未发现有惊恐发作史。

结论

这些结果对惊恐发作在广场恐惧症发病中所假定的关键致病作用提出了质疑。与临床环境中很少见到无惊恐发作的广场恐惧症的研究结果一致,我们发现这类患者很少寻求专业治疗。

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