Juusola M, French A S
Department of Physiology and Biophysics, Dalhousie University, Halifax, Nova Scotia B3H 4H7, Canada.
J Neurophysiol. 1998 Nov;80(5):2781-4. doi: 10.1152/jn.1998.80.5.2781.
The VS-3 slit-sense organs of the tropical wandering spider Cupiennius salei contain two types of mechanosensory neurons with similar morphology but different adaptation properties. We measured the changes in membrane potential produced by mechanical stimulation and by electric current stimulation in a large number of neurons of both types. No significant differences were found between the passive membrane properties of the two groups, but there were significant differences in the extent and time course of receptor potential adaptation between the two types of neurons. These data, combined with the responses to suprathreshold electrical stimuli, indicate that adaptational differences exist at several stages in these neurons but that active membrane conductances dominate the overall behavior. The passive membrane measurements also indicate that effective voltage clamp of the receptor current at the tips of the sensory dendrites is possible in these neurons.
热带游走蛛（Cupiennius salei）的VS-3狭缝感觉器官包含两种形态相似但适应特性不同的机械感觉神经元。我们在大量这两种类型的神经元中测量了机械刺激和电流刺激所产生的膜电位变化。两组的被动膜特性之间未发现显著差异，但两种类型的神经元在感受器电位适应的程度和时间进程上存在显著差异。这些数据，结合对阈上电刺激的反应，表明这些神经元在几个阶段存在适应差异，但主动膜电导主导了整体行为。被动膜测量还表明，在这些神经元中，在感觉树突尖端对感受器电流进行有效的电压钳制是可行的。
