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慢性髓性白血病加速期16号染色体倒位：1例报告并文献复习

Inversion of chromosome 16 in accelerated phase of chronic myeloid leukaemia: report of a case and review of the literature.

作者信息

Colović M, Janković G, Bila J, Djordjević V, Wiernik P H

机构信息

Institute of Hematology, University Clinical Center, Belgrade, Yugoslavia.

出版信息

Med Oncol. 1998 Sep;15(3):199-201. doi: 10.1007/BF02821939.

DOI:10.1007/BF02821939
PMID:9819797
Abstract

A patient with a Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) developed a blast crisis (FAB subtype AML-M2) without a monocytic involvement. Karyotype showed the presence of inv(16)(p13;q22) in addition to Ph, in 16/20 marrow metaphases.

摘要

一名费城染色体阳性（Ph+）慢性髓性白血病（CML）患者发生了原始细胞危象（FAB亚型AML-M2），无单核细胞受累。核型分析显示，在20个骨髓中期细胞中，有16个除了有Ph染色体外，还存在inv(16)(p13;q22)。

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本文引用的文献

1
Early transformation to acute myeloblastic leukaemia with the acquisition of inv(16) in Ph positive chronic granulocytic leukaemia.伴有inv(16)获得的Ph阳性慢性粒细胞白血病早期转化为急性髓细胞白血病
Leuk Res. 1997 May;21(5):473-4. doi: 10.1016/s0145-2126(97)00070-2.
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The biological significance of the multidrug resistance gene MRP in inversion 16 leukemias.多药耐药基因MRP在16号染色体倒位白血病中的生物学意义。
Leuk Lymphoma. 1996 Feb;20(5-6):357-64. doi: 10.3109/10428199609052416.
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Heterogeneity in CBF beta/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia.
Coexistence of p210 and CBFβ-MYH11 fusion genes in myeloid leukemia: A report of 4 cases.
髓系白血病中p210和CBFβ-MYH11融合基因的共存：4例报告
Oncol Lett. 2017 Nov;14(5):5171-5178. doi: 10.3892/ol.2017.6812. Epub 2017 Aug 24.
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Myeloid neoplasms with concurrent BCR-ABL1 and CBFB rearrangements: A series of 10 cases of a clinically aggressive neoplasm.同时伴有BCR-ABL1和CBFB重排的髓系肿瘤：一组10例具有临床侵袭性的肿瘤。
Am J Hematol. 2017 Jun;92(6):520-528. doi: 10.1002/ajh.24710. Epub 2017 Apr 6.
急性髓性白血病中由inv(16)(p13q22)和t(16;16)(p13;q22)编码的CBFβ/MYH11融合信息的异质性。
Blood. 1995 Jun 15;85(12):3695-703.
4
Detection of CBFB/MYH11 transcripts in patients with inversion and other abnormalities of chromosome 16 at presentation and remission.初诊及缓解期16号染色体倒位及其他异常患者中CBFB/MYH11转录本的检测
Br J Haematol. 1995 Sep;91(1):104-8. doi: 10.1111/j.1365-2141.1995.tb05253.x.
5
Inversion of chromosome 16 with the Philadelphia chromosome in acute myelomonocytic leukemia with eosinophilia. Report of two cases.伴有嗜酸性粒细胞增多的急性粒单核细胞白血病中16号染色体倒位与费城染色体。两例报告。
Cancer Genet Cytogenet. 1992 Jan;58(1):29-34. doi: 10.1016/0165-4608(92)90129-v.
6
Inversion of chromosome 16 and bone marrow eosinophilia in a myelomonocytic transformation of chronic myeloid leukemia.慢性髓性白血病髓单核细胞转化中16号染色体倒位与骨髓嗜酸性粒细胞增多
Cancer Genet Cytogenet. 1992 Jul 15;61(2):197-200. doi: 10.1016/0165-4608(92)90086-n.
7
Inversion of chromosome 16 and dysplastic eosinophils in accelerated phase of chronic myeloid leukemia.慢性髓性白血病加速期16号染色体倒位及发育异常嗜酸性粒细胞
Leukemia. 1992 May;6(5):381-4.
8
Acute myelomonocytic leukemia with inv(16)(p13q22) complicating Philadelphia chromosome positive chronic myeloid leukemia.伴有inv(16)(p13q22)的急性粒单核细胞白血病并发费城染色体阳性慢性髓性白血病。
Cancer Genet Cytogenet. 1992 Mar;59(1):35-8. doi: 10.1016/0165-4608(92)90154-z.
9
Temporal association of marrow eosinophilia with inversion of chromosome 16 in recurrent blast crises of chronic myelogenous leukemia.慢性粒细胞白血病复发急变期骨髓嗜酸性粒细胞增多与16号染色体倒位的时间相关性。
Cancer Genet Cytogenet. 1992 Sep;62(2):134-9. doi: 10.1016/0165-4608(92)90251-3.