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成年大鼠内嗅皮质损伤后齿状回的同源传入神经再支配

Reinnervation of dentate gyrus by homologous afferents following entorhinal cortical lesions in adult rats.

作者信息

Steward O

出版信息

Science. 1976 Oct 22;194(4263):426-8. doi: 10.1126/science.982024.

Abstract

Granule cells of the rat dentate gyrus which are denervated by unilateral destruction of the entorhinal cortex are reinnervated in part by proliferation of surviving pathways from the contralateral entorhinal cortex. The cells of origin of these lesion-induced projections were identified by retrograde labeling with horseradish peroxidase and were the same cell type which normally project to the ipsilateral dentate gyrus

摘要

通过单侧破坏内嗅皮质使大鼠齿状回颗粒细胞去神经支配后,对侧内嗅皮质存活通路的增殖可使这些颗粒细胞部分重新获得神经支配。用辣根过氧化物酶逆行标记法确定了这些损伤诱导投射的起源细胞,它们与正常投射至同侧齿状回的细胞类型相同。

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