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成年大鼠内嗅皮质损伤后齿状回的同源传入神经再支配

Reinnervation of dentate gyrus by homologous afferents following entorhinal cortical lesions in adult rats.

作者信息

Steward O

出版信息

Science. 1976 Oct 22;194(4263):426-8. doi: 10.1126/science.982024.

DOI:10.1126/science.982024
PMID:982024
Abstract

Granule cells of the rat dentate gyrus which are denervated by unilateral destruction of the entorhinal cortex are reinnervated in part by proliferation of surviving pathways from the contralateral entorhinal cortex. The cells of origin of these lesion-induced projections were identified by retrograde labeling with horseradish peroxidase and were the same cell type which normally project to the ipsilateral dentate gyrus

摘要

通过单侧破坏内嗅皮质使大鼠齿状回颗粒细胞去神经支配后,对侧内嗅皮质存活通路的增殖可使这些颗粒细胞部分重新获得神经支配。用辣根过氧化物酶逆行标记法确定了这些损伤诱导投射的起源细胞,它们与正常投射至同侧齿状回的细胞类型相同。

相似文献

1
Reinnervation of dentate gyrus by homologous afferents following entorhinal cortical lesions in adult rats.成年大鼠内嗅皮质损伤后齿状回的同源传入神经再支配
Science. 1976 Oct 22;194(4263):426-8. doi: 10.1126/science.982024.
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Identification of the cells of origin of a central pathway which sprouts following lesions in mature rats.成熟大鼠损伤后萌发的中枢通路起源细胞的鉴定。
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Sprouting of central noradrenergic fibers in the dentate gyrus following combined lesions of its entorhinal and septal afferents.内嗅和隔区传入纤维联合损伤后齿状回中脑去甲肾上腺素能纤维的发芽
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Behavioral correlates of denervation and reinnervation of the hippocampal formation of the rat: recovery of alternation performance following unilateral entorhinal cortex lesions.大鼠海马结构去神经支配和再支配的行为相关性:单侧内嗅皮层损伤后交替行为表现的恢复
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An autoradiographic study of the development of the entorhinal and commissural afferents to the dentate gyrus of the rat.
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Lesion-induced synapse reorganization in the hippocampus of cats: sprouting of entorhinal, commissural/associational, and mossy fiber projections after unilateral entorhinal cortex lesions, with comments on the normal organization of these pathways.猫海马体中损伤诱导的突触重组:单侧内嗅皮层损伤后内嗅、连合/联合及苔藓纤维投射的发芽,并对这些通路的正常组织进行评论
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Collateral projections of cells in the surviving entorhinal area which reinnervate the dentate gyrus of the rat following unilateral entorhinal lesions.在单侧内嗅皮层损伤后重新支配大鼠齿状回的存活内嗅区域细胞的侧支投射。
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Cells of origin of entorhinal cortical afferents to the hippocampus and fascia dentata of the rat.大鼠海马和齿状回的内嗅皮质传入纤维的起源细胞。
J Comp Neurol. 1976 Oct 1;169(3):347-70. doi: 10.1002/cne.901690306.
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Evidence for collateral projections by neurons in Ammon's horn, the dentate gyrus, and the subiculum: a multiple retrograde labeling study in the rat.海马角、齿状回和海马下托中神经元的侧支投射证据:大鼠的多重逆行标记研究
J Neurosci. 1981 May;1(5):548-59. doi: 10.1523/JNEUROSCI.01-05-00548.1981.

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Crossed Entorhino-Dentate Projections Form and Terminate With Correct Layer-Specificity in Organotypic Slice Cultures of the Mouse Hippocampus.在小鼠海马体的器官型切片培养物中,交叉的内嗅 - 齿状投射以正确的层特异性形成并终止。
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