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顺势疗法山金车的疗效:安慰剂对照临床试验的系统评价

Efficacy of homeopathic arnica: a systematic review of placebo-controlled clinical trials.

作者信息

Ernst E, Pittler M H

机构信息

Department of Complementary Medicine, School of Postgraduate Medicine and Health Sciences, University of Exeter, England, United Kingdom.

出版信息

Arch Surg. 1998 Nov;133(11):1187-90. doi: 10.1001/archsurg.133.11.1187.

DOI:10.1001/archsurg.133.11.1187
PMID:9820349
Abstract

BACKGROUND

The efficacy of homeopathic remedies has remained controversial. The homeopathic remedy most frequently studied in placebo-controlled clinical trials is Arnica montana.

OBJECTIVE

To systematically review the clinical efficacy of homeopathic arnica.

MATERIALS AND METHODS

Computerized literature searches were performed to retrieve all placebo-controlled studies on the subject. The following databases were searched: MEDLINE, EMBASE, CISCOM, and the Cochrane Library. Data were extracted in a predefined, standardized fashion independently by both authors. There were no restrictions on the language of publications.

RESULTS

Eight trials fulfilled all inclusion criteria. Most related to conditions associated with tissue trauma. Most of these studies were burdened with severe methodological flaws. On balance, they do not suggest that homeopathic arnica is more efficacious than placebo.

CONCLUSION

The claim that homeopathic arnica is efficacious beyond a placebo effect is not supported by rigorous clinical trials.

摘要

背景

顺势疗法药物的疗效一直存在争议。在安慰剂对照临床试验中研究最频繁的顺势疗法药物是山金车花。

目的

系统评价顺势疗法山金车花的临床疗效。

材料与方法

进行计算机文献检索以检索所有关于该主题的安慰剂对照研究。检索了以下数据库:医学文献数据库(MEDLINE)、荷兰医学文摘数据库(EMBASE)、顺势疗法综合信息系统(CISCOM)和考克兰图书馆。两位作者均以预先定义的标准化方式独立提取数据。对出版物的语言没有限制。

结果

八项试验符合所有纳入标准。大多数试验涉及与组织创伤相关的病症。这些研究大多存在严重的方法学缺陷。总体而言,它们并未表明顺势疗法山金车花比安慰剂更有效。

结论

严格的临床试验不支持顺势疗法山金车花除安慰剂效应外还有效的说法。

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Efficacy of homeopathic arnica: a systematic review of placebo-controlled clinical trials.顺势疗法山金车的疗效:安慰剂对照临床试验的系统评价
Arch Surg. 1998 Nov;133(11):1187-90. doi: 10.1001/archsurg.133.11.1187.
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[On the effectiveness of the homeopathic remedy Arnica montana].[论顺势疗法药物山金车的疗效]
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