Lanzl I M, Augsburger J J, Hertle R W, Rapuano C, Correa-Melling Z, Santa Cruz C
Glaucoma Service, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Cornea. 1998 Nov;17(6):604-6. doi: 10.1097/00003226-199811000-00006.
Limbal dermoids usually involve corneal stroma and more rarely might extend into the anterior chamber. Depending on the size and amount of penetration of the lesion, different therapeutic approaches are indicated. Depth information is difficult to obtain by slit-lamp examination because the structure is opaque. We investigated the use of ultrasound biomicroscopic (UBM) examination for surgical planning in limbal dermoids.
The UBM (Zeiss Humphrey) with its 50-MHz probe was used for preoperative evaluation of the depth of penetration in two cases of infantile limbal dermoid. Histology specimens of the lesion corresponding to the UBM images were obtained.
UBM was able to distinguish normal cornea from the more sonolucent lesion. Presence or absence of Descemet's membrane could be identified. Depth of involvement of limbal dermoids could be assessed.
UBM is able to assess depth involvement of opaque corneal lesions such as limbal dermoids. Because planning of the surgical approach in these cases is facilitated by preoperative knowledge about the depth of penetration of these opaque lesions, UBM can be regarded as a helpful tool in the clinical management.
角膜缘皮样瘤通常累及角膜基质，很少会延伸至前房。根据病变的大小和穿透程度，需要采取不同的治疗方法。由于该结构不透明，通过裂隙灯检查很难获得深度信息。我们研究了超声生物显微镜（UBM）检查在角膜缘皮样瘤手术规划中的应用。
使用配备50MHz探头的UBM（蔡司汉弗莱）对2例婴儿角膜缘皮样瘤进行术前穿透深度评估。获取与UBM图像对应的病变组织学标本。
UBM能够区分正常角膜与透声性更强的病变。可以确定后弹力层是否存在。能够评估角膜缘皮样瘤的累及深度。
UBM能够评估不透明角膜病变（如角膜缘皮样瘤）的累及深度。由于术前了解这些不透明病变的穿透深度有助于此类病例的手术方案规划，因此UBM可被视为临床管理中的有用工具。
