Hendriks D M, Barnard S B
S Afr J Med Sci. 1976;41(3):233-8.
Extirpation of the endolymphatic anlage of the ear vesicle or that part of the ear placode which develops into the endolymphatic anlage in chick embryos, resulted in the absence of the endolymphatic system. In specimens of which the endolymphatic anlage was removed on the fourth day, healing of the wound was completed soon after the fifth day of incubation. Most of these experimental animals developed endolymphatic hydrops at a later stage. However, where healing was delayed after the fifth day, the open wound acted as an escape route for the endolymph (thus preventing further closure) which at that stage (or soon after) reached an appreciable volume.
切除鸡胚耳泡的内淋巴原基或耳基板中发育为内淋巴原基的部分，会导致内淋巴系统缺失。在第四天切除内淋巴原基的标本中，伤口在孵化第五天后不久就愈合了。这些实验动物中的大多数在后期出现了内淋巴积水。然而，在第五天后愈合延迟的情况下，开放的伤口成为内淋巴的逃逸通道（从而阻止进一步闭合），在那个阶段（或之后不久）内淋巴达到了可观的体积。
