局部抗炎治疗对激光小梁成形术长期疗效的影响。氟米龙-激光小梁成形术研究组。
Effect of topical anti-inflammatory treatment on the long-term outcome of laser trabeculoplasty. Fluorometholone-Laser Trabeculoplasty Study Group.
作者信息
Kim Y Y, Glover B K, Shin D H, Lee D, Frenkel R E, Abreu M M
机构信息
Kresge Eye Institute, Wayne State University School of Medicine, Detroit, Michigan 48201-1423, USA.
出版信息
Am J Ophthalmol. 1998 Nov;126(5):721-3. doi: 10.1016/s0002-9394(98)00177-9.
PURPOSE
To investigate the effect of anti-inflammatory treatment on the long-term outcome of argon laser trabeculoplasty, we extended the short-term study of the Fluorometholone-Laser Trabeculoplasty Study Group.
METHODS
Among the chronic open-angle glaucoma patients randomly assigned to the 0.25% fluorometholone or placebo eyedrops four times daily before and after argon laser trabeculoplasty in the Fluorometholone-Laser Trabeculoplasty Study, the long-term records of 27 patients (13 eyes in the fluorometholone group and 14 eyes in the placebo group) were available for our review and analysis.
RESULTS
There were no statistically significant differences in the success rate of argon laser trabeculoplasty between the fluorometholone and control groups over the follow-up period of 4.6 +/- 3.4 years.
CONCLUSION
While it decreased ocular inflammation and discomfort during the early postoperative period, peri-argon laser trabeculoplasty use of a topical corticosteroid did not influence the long-term intraocular pressure outcome of argon laser trabeculoplasty.
目的
为了研究抗炎治疗对氩激光小梁成形术长期疗效的影响，我们扩展了氟米龙-激光小梁成形术研究组的短期研究。
方法
在氟米龙-激光小梁成形术研究中，将慢性开角型青光眼患者随机分为两组，分别在氩激光小梁成形术前和术后每天4次滴用0.25%氟米龙滴眼液或安慰剂滴眼液。我们可获取27例患者（氟米龙组13只眼，安慰剂组14只眼）的长期记录用于回顾和分析。
结果
在4.6±3.4年的随访期内，氟米龙组和对照组氩激光小梁成形术的成功率无统计学显著差异。
结论
虽然局部使用皮质类固醇在氩激光小梁成形术围手术期可减轻术后早期的眼部炎症和不适，但并未影响氩激光小梁成形术的长期眼压控制效果。
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