Sastre-Janer F A, Regis J, Belin P, Mangin J F, Dormont D, Masure M C, Remy P, Frouin V, Samson Y
CEA, Service Hospitalier Frédéric Joliot, DSV/DRM, Orsay, France.
Cereb Cortex. 1998 Oct-Nov;8(7):641-7. doi: 10.1093/cercor/8.7.641.
One way to improve our understanding of cortical anatomy is to visualize the three-dimensional (3D) shape of the cerebral sulci which is normally hidden. Here, we reconstructed the 3D morphology of the central sulcus (CS) in 17 normal subjects, using conventional magnetic resonance images and dedicated software. We found that the 3D morphology was remarkably consistent in all central sulci. Our analyses revealed three different regions (upper, middle and lower), which were easily identifiable by morphological criteria and sharply interconnected in the reconstructed CS. These morphological regions appear to have a strong functional significance, since the middle region corresponded precisely to the 'hand area', as verified by hand vibration positron emission tomography activation studies in eight cases. These data suggest that the 3D anatomy of the cerebral cortex may facilitate sulcal recognition, and sulcal subdivision into smaller morphological elements, bearing remarkable relationships with functional cortical maps.
提高我们对皮质解剖结构理解的一种方法是可视化通常隐藏的大脑沟回的三维（3D）形状。在此，我们使用传统磁共振图像和专用软件重建了17名正常受试者中央沟（CS）的三维形态。我们发现所有中央沟的三维形态都非常一致。我们的分析揭示了三个不同区域（上部、中部和下部），通过形态学标准很容易识别，并且在重建的中央沟中紧密相连。这些形态学区域似乎具有很强的功能意义，因为中部区域恰好对应于“手部区域”，这在8例手部振动正电子发射断层扫描激活研究中得到了证实。这些数据表明，大脑皮质的三维解剖结构可能有助于沟回识别，并将沟回细分为更小的形态学元素，这些元素与皮质功能图谱有着显著的关系。
