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雪貂(Mustela putorius furo)中与肾上腺皮质病变相关的前列腺囊性疾病。

Cystic prostatic disease associated with adrenocortical lesions in the ferret (Mustela putorius furo).

作者信息

Coleman G D, Chavez M A, Williams B H

机构信息

Division of Pathology, Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA.

出版信息

Vet Pathol. 1998 Nov;35(6):547-9. doi: 10.1177/030098589803500612.

DOI:10.1177/030098589803500612
PMID:9823599
Abstract

A review of case materials at the Armed Forces Institute of Pathology identified six cases of prostatitis in domestic ferrets (Mustela putorius furo). Five of these ferrets (83%) had one or more cysts and the remaining ferret had a paraprostatic cyst. Three of the six ferrets (50%) exhibited various degrees of prostatic squamous metaplasia. Inflammation ranged from subacute to chronic-active or pyogranulomatous. In addition to the prostatic lesions, hyperplastic and/or neoplastic adrenocortical lesions were present in 4/6 (66%) ferrets; 1/6 (17%) ferrets had previously been clinically diagnosed with adrenal gland-associated endocrinopathy. The remaining ferret had previously had the right adrenal gland removed, but the reason for the removal is unknown. Based upon the histologic findings in these six ferrets, there appears to be an association between proliferative adrenal lesions and cystic prostatitis in domestic ferrets.

摘要

美国武装部队病理研究所对病例资料进行回顾,确定了6例家养雪貂(Mustela putorius furo)前列腺炎病例。其中5只雪貂(83%)有一个或多个囊肿,其余1只雪貂有前列腺旁囊肿。6只雪貂中有3只(50%)表现出不同程度的前列腺鳞状化生。炎症范围从亚急性到慢性活动性或脓性肉芽肿性。除前列腺病变外,4/6(66%)的雪貂存在增生性和/或肿瘤性肾上腺皮质病变;1/6(17%)的雪貂先前临床诊断为肾上腺相关内分泌病。其余1只雪貂先前已切除右侧肾上腺,但切除原因不明。基于这6只雪貂的组织学发现,家养雪貂增生性肾上腺病变与囊性前列腺炎之间似乎存在关联。

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Issues to consider for preparing ferrets as research subjects in the laboratory.
将雪貂准备为实验室研究对象时需要考虑的问题。
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