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慢性胰腺炎、原发性胆汁性肝硬化和系统性硬化症关联的首例报告。

First report of association of chronic pancreatitis, primary biliary cirrhosis, and systemic sclerosis.

作者信息

Hastier P, Buckley M J, Le Gall P, Bellon S, Dumas R, Delmont J

机构信息

Department of Hepato-Gastroenterology, L'Archet II Hospital, CHU, Nice, France.

出版信息

Dig Dis Sci. 1998 Nov;43(11):2426-8. doi: 10.1023/a:1026673930030.

DOI:10.1023/a:1026673930030
PMID:9824129
Abstract

We report an original observation of chronic pancreatitis associated with primary biliary cirrhosis and systemic sclerosis. The diagnosis of each of these conditions was unequivocally confirmed. Pancreatic involvement in this case was asymptomatic. The association of chronic pancreatitis with primary biliary cirrhosis has been previously reported and pancreatitis has been associated with other autoimmune disorders. We hypothesize about the underlying pathogenic mechanisms of chronic pancreatitis in our case.

摘要

我们报告了一例原发性胆汁性肝硬化和系统性硬化症相关的慢性胰腺炎的原始观察病例。这三种疾病的诊断均得到明确证实。该病例中胰腺受累无明显症状。慢性胰腺炎与原发性胆汁性肝硬化的关联此前已有报道，且胰腺炎还与其他自身免疫性疾病有关。我们对该病例中慢性胰腺炎的潜在致病机制进行了推测。

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