King R W
Gordon McKay Laboratory, Division of Engineering and Applied Sciences.
IEEE Eng Med Biol Mag. 1998 Nov-Dec;17(6):67-73; discussion 73-8. doi: 10.1109/51.731324.
A detailed examination of the scientific foundations contained in a number of recent articles has revealed some serious errors. The careful application of advanced mathematical-physical methods to study the penetration of externally applied electric fields into the organs and cells of the human body has obtained new and significant results [8, 9, 32]. Specifically, Eqs. (11) and (12) establish a definite relationship between an incident low-frequency electric field and the current, current density, and electric field induced in the body when the arms are in contact with it and the incident field is parallel to its length. Corresponding formulas with the arms raised are available [10] as are formulas for the current density and electric field in the organs of the body [9]. It is these currents and electric fields that must be used by biomedical research workers to determine their effect on living cells. The proposed interpretation of epidemiological data [31] indicates a risk of leukemia in children when the incident 50-60-Hz electric field generated by a high-voltage transmission line is Einc > or = 61 V/m. (23). The corresponding maximum electric field at approximately 10 m from a 440-kV transmission line is Einc approximately 2100 V/m [8, 9]. The electric fields induced in the different organs of the body by these electric fields are in the range 25.2 < or = E1z < or = 119 microV/m for Einc2z = 61 V/m and 0.87 < or = E1z < or = 4.1 mV/m for Einc2z = 2100 V/m [9]. These are in the range of applied fields in in vitro experiments, which showed significant effects on cells [4], and should serve as guidelines for such experiments.
对近期一些文章中所包含的科学基础进行的详细审视揭示了一些严重错误。将先进的数学物理方法审慎地应用于研究外部施加的电场对人体器官和细胞的穿透情况，已取得了新的重要成果[8, 9, 32]。具体而言，式(11)和式(12)确立了入射低频电场与当手臂与之接触且入射场平行于其长度时人体中感应的电流、电流密度和电场之间的明确关系。手臂抬起时的相应公式见[10]，人体器官中电流密度和电场的公式见[9]。生物医学研究人员必须依据这些电流和电场来确定它们对活细胞的影响。对流行病学数据[31]的拟议解释表明，当高压输电线产生的入射50 - 60赫兹电场为Einc≥61 V/m时，儿童患白血病存在风险(23)。距440千伏输电线约10米处的相应最大电场为Einc约2100 V/m[8, 9]。对于Einc2z = 61 V/m，这些电场在人体不同器官中感应出的电场范围为25.2≤E1z≤119微伏/米；对于Einc2z = 2100 V/m，感应电场范围为0.87≤E1z≤4.1毫伏/米[9]。这些处于体外实验中施加电场的范围内，体外实验已表明对细胞有显著影响[4]，并且应作为此类实验的指导原则。
