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[隐匿性原发性肿瘤颈部淋巴结癌转移:生存率取决于肿瘤定位、分期、组织学及治疗方法(48例患者)]

[Carcinoma metastases in neck lymph nodes in occult primary tumor: survival rate depending from localization, stadium, histology and therapeutic method (48 patients)].

作者信息

Glanzmann C, Aberle H, Horst W

出版信息

Strahlentherapie. 1976 Oct;152(4):345-51.

PMID:982486
Abstract

In patients with metastatic cancer in cervical nodes without evidence of a primary cancer, radiation therapy eventually supplemented by surgery is indicated. The treated volume should include the regions of the possible primary (pharynx, base of tongue, tonsil) besides the cervical node regions. Five-year cure rates are: about 40% in cases with cervical nodes only, more than 50% in cases with cervical nodes in one region only and not fixed, less than 10% in cases with supraclavicular nodes. In about 30% a primary tumor is found later. About 50% of these primaries is located in the supraclavicular volume and about 50% is located in the infraclavicular volume. In cases with supraclavicular nodes the majority of the primary tumors are located in the infraclavicular colume.

摘要

对于颈部淋巴结有转移癌但无原发癌证据的患者,建议采用放射治疗,最终辅以手术。治疗范围应包括除颈部淋巴结区域外可能的原发部位(咽、舌根、扁桃体)。五年治愈率为:仅颈部淋巴结转移的病例约为40%,仅一个区域且未固定的颈部淋巴结转移病例超过50%,有锁骨上淋巴结转移的病例低于10%。约30%的患者后来发现了原发肿瘤。这些原发肿瘤中约50%位于锁骨上区域,约50%位于锁骨下区域。有锁骨上淋巴结转移的病例中,大多数原发肿瘤位于锁骨下区域。

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