Allen D N, Huegel S G, Seaton B E, Goldstein G, Gurklis J A, van Kammen D P
VA Pittsburgh Healthcare System, Highland Drive Division, PA 15206, USA.
Schizophr Res. 1998 Nov 9;34(1-2):87-94. doi: 10.1016/s0920-9964(98)00090-5.
Although factor scores are commonly used to interpret the Weschsler Adult Intelligence Scale--Revised (WAIS-R), the WAIS-R factor structure has not been investigated in patients with schizophrenia. We used confirmatory factor analysis (CFA) to examine five latent construct models in 169 males with schizophrenia. The WAIS-R standardization sample (ages 35-44; n = 250) was used as a comparison group. For both groups, all model fit indexes used to determine model adequacy supported models composed of Verbal Comprehension (VC), Perceptual Organization (PO) and Freedom from Distractibility (FFD) factors. However, the Digit Symbol subtest loaded on both the PO and FFD factors for patients with schizophrenia but only on the FFD factor for the WAIS-R standardization sample. Patients with schizophrenia performed significantly worse on the FFD and PO factors compared to the VC factor, reflecting the well-characterized attention and problem solving deficits associated with schizophrenia. Also, patients with schizophrenia performed significantly worse than the WAIS-R sample on all factors. These results provide support for the validity of the WAIS-R factors in patients with schizophrenia.
尽管因子分数通常用于解释韦氏成人智力量表修订版（WAIS-R），但尚未对精神分裂症患者的WAIS-R因子结构进行研究。我们使用验证性因子分析（CFA）对169名男性精神分裂症患者的五个潜在结构模型进行了检验。WAIS-R标准化样本（年龄35 - 44岁；n = 250）用作对照组。对于两组而言，所有用于确定模型适用性的模型拟合指数均支持由言语理解（VC）、知觉组织（PO）和抗干扰能力（FFD）因子组成的模型。然而，数字符号分测验在精神分裂症患者中同时加载于PO和FFD因子，但在WAIS-R标准化样本中仅加载于FFD因子。与VC因子相比，精神分裂症患者在FFD和PO因子上的表现明显更差，这反映了与精神分裂症相关的典型注意力和解决问题能力缺陷。此外，精神分裂症患者在所有因子上的表现均明显比WAIS-R样本差。这些结果为WAIS-R因子在精神分裂症患者中的有效性提供了支持。
