Allen D N, Aldarondo F, Goldstein G, Huegel S G, Gilbertson M, van Kammen D P
VA Pittsburgh Healthcare System, PA 15206, USA.
Assessment. 1998 Dec;5(4):365-74. doi: 10.1177/107319119800500406.
Validity studies of neuropsychological tests have typically examined individuals with neurological disorders. The present study was designed to investigate the construct validity of neuropsychological measures in patients with schizophrenia. We used Wechsler Adult Intelligence Scale Revised (WAIS-R) factor scores that were generated from the population of interest as marker variables in the present analysis. The current study included 39 patients with schizophrenia who were evaluated with a battery of neuropsychological tests assessing attention, memory, and abstract reasoning abilities. Pearson correlations indicated significant relationships between (a) WAIS-R Verbal Comprehension factor and tests of sustained attention, verbal memory and remote memory; (b) WAIS-R Perceptual Organization factor and tests of visual memory and abstraction and problem solving; and (c) WAIS-R Freedom From Distractibility factor and neuropsychological measures of attention and concentration. These results provide support for the construct validity of the neuropsychological tests in patients with schizophrenia, and indicate that these tests evaluate essentially the same constructs in patients with schizophrenia as they do for patients with structural neurological disorders.
神经心理学测试的效度研究通常针对患有神经障碍的个体。本研究旨在调查精神分裂症患者神经心理学测量的结构效度。在本分析中，我们使用了从目标人群中得出的韦氏成人智力量表修订版（WAIS-R）因子得分作为标记变量。当前研究纳入了39名精神分裂症患者，他们接受了一系列评估注意力、记忆力和抽象推理能力的神经心理学测试。皮尔逊相关性表明：（a）WAIS-R言语理解因子与持续注意力测试、言语记忆测试和远期记忆测试之间存在显著关系；（b）WAIS-R知觉组织因子与视觉记忆测试、抽象及解决问题能力测试之间存在显著关系；（c）WAIS-R注意力分散度因子与注意力和专注力的神经心理学测量之间存在显著关系。这些结果为神经心理学测试在精神分裂症患者中的结构效度提供了支持，并表明这些测试在精神分裂症患者中所评估的结构与在患有结构性神经障碍的患者中所评估的基本相同。
