Supe S J, Rao S M, Sawant S G, Bisht J S
Strahlentherapie. 1976 Oct;152(4):385-94.
The concept of NSD has been modified into TDF's by Orton and Ellis and CRE's by Kirk et al. It was aimed to study the variability of these new concepts on the exponents of time and number of fractions. It was found that TDF has larger variation with the exponents compared to that of CRE. The use of CRE and NSD for solving the treatment scheduling problems or for intercomparison of various regimes has been simplified by providing readymade estimation of CRE for various doses/fraction with increasing number of fractions. As there is increasing evidence for the change of exponents J and H, nomograms are presented to determine the CRE for various values of J and H. The variation of decay correction factors with the exponent H is also evaluated and is presented. This will help various radiotherapists to use CRE and the decay correction factors consistent with their clinical findings.
NSD的概念已被奥顿和埃利斯修改为TDF，被柯克等人修改为CRE。目的是研究这些新概念在时间指数和分次次数方面的变异性。结果发现，与CRE相比，TDF随指数的变化更大。通过提供各种剂量/分次（随着分次次数增加）的CRE现成估计值，简化了使用CRE和NSD来解决治疗计划问题或对各种治疗方案进行相互比较的过程。由于越来越多的证据表明指数J和H会发生变化，因此给出了列线图以确定不同J和H值下的CRE。还评估并给出了衰变校正因子随指数H的变化情况。这将有助于各种放射治疗师使用与他们临床发现一致的CRE和衰变校正因子。
