Razzak M A, Hassaballa N
Tropenmed Parasitol. 1976 Sep;27(3):343-8.
Using heat-treated 51Cr tagged red cells radionuclide scanning of the spleen was performed in 17 patients suffering from hepatosplenic schistosomiasis. Furthermore, following the injection of the thermally damaged erythrocytes, the disappearance half time of radioactivity was calculated from splenic radioactivity build-up tracings. Out of the 17 bilharzial patients examined, 12 had disappearance half times shorter than the lowest limit obtained in normal subjects, denoting exaggerated splenic trapping of heat-treated red cells. Analysis of the results showed that the rate of trapping of heated erythrocytes was more rapid in patients presenting with bigger splenic enlargement, as well as in those having more marked anemia. This might be taken to indicate a possible link between the occurrence of anemia and the spleen in schistosomiasis. By radionuclide scanning, the bilharzial spleen was bigger than normal. In addition, the splenic shadow appeared to be either oval, triangular or kidney shaped. In 9 patients, the distribution of radioactivity was homogenous, with decrease in the density towards the periphery. In the remaining 8 cases, patchy distribution of radioactivity was observed. Mottling was more marked in the huge spleens as well as in the presence of severe anemia.
对17例肝脾型血吸虫病患者进行了热处理的51Cr标记红细胞脾放射性核素扫描。此外，在注入热损伤红细胞后，根据脾脏放射性积聚曲线计算放射性消失半衰期。在检查的17例血吸虫病患者中，有12例的消失半衰期短于正常受试者的最低值，表明脾脏对热处理红细胞的捕获增强。结果分析显示，脾脏肿大较明显以及贫血较显著的患者，热红细胞的捕获速率更快。这可能表明血吸虫病中贫血的发生与脾脏之间可能存在联系。通过放射性核素扫描，血吸虫病患者的脾脏比正常人大。此外，脾脏影像呈椭圆形、三角形或肾形。9例患者放射性分布均匀，密度向周边降低。其余8例观察到放射性呈斑片状分布。在巨大脾脏以及严重贫血患者中，斑纹更为明显。
