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[类风湿关节炎和红斑狼疮患者血浆中的血管性血友病因子]

[Von Willebrand factor in plasma of patients with rheumatoid arthritis and lupus erythematosus].

作者信息

Paczuski R, Iwan-Zietek I, Kotschy M, Bielawska J, Sadkiewicz S

机构信息

Katedry i Zakładu Patofizjologii Akademii Medycznej w Bydgoszczy.

出版信息

Pol Merkur Lekarski. 1998 May;4(23):254-6.

PMID:9825655
Abstract

The plasma levels of von Willebrand factor antigen (vWf:Ag) were evaluated for groups of 31 patients with rheumatoid arthritis and 34 patients with lupus erythematosus. The control group consisted of 34 healthy volunteers. In both groups the levels of vWf:Ag were increased to 243% and 240% respectively. The levels of vWf:Ag were also analysed statistically for the correlation with age of patients, time of the duration of disease and fibrinogen levels. No correlations were found. Obtained results suggest that measurements of vWf:Ag concentrations may be useful as potential marker of endothelial injury.

摘要

对31例类风湿性关节炎患者和34例红斑狼疮患者进行了血管性血友病因子抗原(vWf:Ag)的血浆水平评估。对照组由34名健康志愿者组成。两组中vWf:Ag水平分别升高至243%和240%。还对vWf:Ag水平与患者年龄、病程时间和纤维蛋白原水平的相关性进行了统计学分析。未发现相关性。所得结果表明,vWf:Ag浓度的测量可能作为内皮损伤的潜在标志物有用。

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