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多发性硬化症中稳态模式视觉诱发电位的波幅降低。

Decreased amplitude of steady state pattern visually evoked cortical potentials in multiple sclerosis.

作者信息

Fujimoto N, Adachi-Usami E

机构信息

Department of Ophthalmology, Chiba University School of Medicine, Japan.

出版信息

Acta Ophthalmol Scand. 1998 Oct;76(5):625-6. doi: 10.1034/j.1600-0420.1998.760525.x.

Abstract

PURPOSE

We studied the amplitude of steady state (St) PVECP using the amplitude ratio to transient (Tr) PVECP clinically in patients with multiple sclerosis.

METHODS

Case report. A 25-year-old woman had multiple sclerosis without optic neuritis. She had normal vision and visual fields. She was followed by both St and TrPVECP. Statistical analysis. Patients with multiple sclerosis and no optic neuritis were retrospectively studied for both Tr and StVECP.

RESULTS

Six months later, she showed a decreased ratio in the left eye, corresponding to abnormalities in the center of the visual field. The peak latency of TrPVECP remained normal in both eyes. A decreased ratio was found in 27% of patients with multiple sclerosis and no optic neuritis.

CONCLUSIONS

Not only Tr, but StPVECP should be recorded in patients with multiple sclerosis and normal vision to detect abnormalities in the visual pathway.

摘要

目的

我们在多发性硬化症患者中,通过稳态(St)图形视觉诱发电位(PVECP)与瞬态(Tr)PVECP的幅度比,对稳态PVECP的幅度进行了临床研究。

方法

病例报告。一名25岁女性患有无视神经炎的多发性硬化症。她视力和视野正常。对其进行了稳态和瞬态PVECP检查。统计分析。对无视神经炎的多发性硬化症患者的瞬态和稳态视觉诱发电位进行回顾性研究。

结果

6个月后,她左眼的比值下降,与视野中心的异常情况相对应。双眼TrPVECP的峰潜伏期仍正常。在无视神经炎的多发性硬化症患者中,27%的患者出现比值下降。

结论

对于视力正常的多发性硬化症患者,不仅应记录TrPVECP,还应记录StPVECP,以检测视觉通路中的异常情况。

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