Crooks B N, Deshpande S A, Hall C, Platt M P, Milligan D W
Newcastle Neonatal Service, Royal Victoria Infirmary, Newcastle upon Tyne.
Arch Dis Child Fetal Neonatal Ed. 1998 Sep;79(2):F150-1. doi: 10.1136/fn.79.2.f150.
Two infants with features of severe beta adrenergic blockade, pericardial effusions, and myocardial hypertrophy were born to mothers receiving long term treatment with oral labetalol for hypertension in pregnancy. Labetalol was implicated in the aetiology of these problems. Pericardial effusion and myocardial hypertrophy have not been associated with labetalol toxicity in neonates.
两名患有严重β-肾上腺素能阻滞、心包积液和心肌肥厚症状的婴儿,其母亲在孕期因高血压接受了长期口服拉贝洛尔治疗。这些问题的病因被认为与拉贝洛尔有关。心包积液和心肌肥厚与新生儿拉贝洛尔毒性并无关联。