Riddle M
Division of Child and Adolescent Psychiatry, Johns Hopkins Medical Institutions, Children's Center, Baltimore, MD 21287-3325, USA.
Br J Psychiatry Suppl. 1998(35):91-6.
Obsessive-compulsive disorder (OCD) is a common psychiatric condition that usually emerges during childhood or adolescence. Over 80% of individuals with OCD have their onset before age 18 years. Epidemiologic studies suggest a prevalence of 1-2% for adolescents.
This article reviews current knowledge of paediatric OCD in the following areas: age of onset, nosology and classification, subtypes, prevalence, aetiology, pathophysiology, assessment, prognosis and treatment.
Essential components of treatment include long-term commitment, care management and illness education. Specific components of treatment include cognitive-behavioural therapy, parent behaviour management training and medication.
The most effective treatments are selective serotonin reuptake inhibitors (e.g. fluvoxamine, sertraline) and exposure/response prevention.
强迫症(OCD)是一种常见的精神疾病,通常在儿童期或青少年期出现。超过80%的强迫症患者在18岁之前发病。流行病学研究表明,青少年中的患病率为1%-2%。
本文综述了儿童强迫症在以下方面的现有知识:发病年龄、疾病分类学和分类、亚型、患病率、病因、病理生理学、评估、预后和治疗。
治疗的基本要素包括长期投入、护理管理和疾病教育。治疗的具体要素包括认知行为疗法、家长行为管理培训和药物治疗。
最有效的治疗方法是选择性5-羟色胺再摄取抑制剂(如氟伏沙明、舍曲林)以及暴露/反应预防。