Vopr Virusol. 1976 May-Jun(3):366-71.
Infection of white random-bred mice and C57B1(6) mice with a culture of R. tsutsugamushi demonstrated that white mice were highly susceptible to the infection which ended in death of the animals and accumulation of rickettsia in the body and necrotization of cell elements of the exudate. Mice of C57B1(6) strain developed acymptomatic infection, rickettsia did not multiply in the peritoneal cavity and exudate cells did not undergo necribiosis. The mechanism of resistance of cells of these mice to the agent requires a further study.
用恙虫病立克次氏体培养物感染白色随机繁殖小鼠和C57B1(6)小鼠,结果表明白色小鼠对该感染高度敏感,感染最终导致动物死亡,立克次氏体在体内积聚,渗出液的细胞成分发生坏死。C57B1(6)品系的小鼠发生无症状感染,立克次氏体不在腹腔内繁殖,渗出液细胞也未发生坏死。这些小鼠细胞对病原体的抵抗机制需要进一步研究。