Bergmans D C, Bonten M J, Stobberingh E E, van Tiel F H, van der Geest S, de Leeuw P W, Gaillard C A
Department of Internal Medicine, University Hospital Maastricht, The Netherlands.
Infect Control Hosp Epidemiol. 1998 Nov;19(11):853-5. doi: 10.1086/647745.
To determine routes of colonization and genotypic variation of Pseudomonas aeruginosa leading to ventilator-associated pneumonia, colonization of the rectum, stomach, oropharynx, and trachea was studied chronologically in 10 patients. Ninety-one isolates of P aeruginosa were genotyped; seven different genotypes were identified. Patients developing ventilator-associated pneumonia caused by P aeruginosa were colonized at multiple body sites and may be colonized with multiple genotypes. The upper respiratory tract is the predominant initial site of colonization with P aeruginosa.
为确定导致呼吸机相关性肺炎的铜绿假单胞菌的定植途径和基因型变异，对10例患者的直肠、胃、口咽和气管定植情况进行了时间顺序研究。对91株铜绿假单胞菌进行了基因分型，鉴定出7种不同的基因型。发生由铜绿假单胞菌引起的呼吸机相关性肺炎的患者在多个身体部位定植，且可能被多种基因型定植。上呼吸道是铜绿假单胞菌定植的主要初始部位。
