Spyrou G, Tzanakos G, Bakas A, Panayiotakis G
University of Patras, School of Medicine, Medical Physics Department, Greece.
Phys Med Biol. 1998 Nov;43(11):3341-57. doi: 10.1088/0031-9155/43/11/012.
We have developed a model using Monte Carlo methods to simulate x-ray mammography. All possible physical processes of interaction of x-rays with matter have been taken into account. A simplified geometry of the mammographic apparatus has been considered along with a software phantom of compressed breast. The phantom may contain inhomogeneities of various compositions and sizes. We have used this model to produce Monte Carlo mammograms under realistic conditions. The validation of the simulation includes both the modelling of physical processes and the production of Monte Carlo mammograms. The first part is accomplished by the demonstration of the coincidence between Monte Carlo and theoretical data, whereas the second is accomplished by the comparison of real mammograms, taken from irradiation of a simplified breast phantom that we have constructed, and Monte Carlo mammograms taken from simulation of the above phantom under the corresponding exposure conditions. The limitations of the model as well as the future use of Monte Carlo mammograms are discussed.
我们利用蒙特卡罗方法开发了一个模型来模拟乳腺X线摄影。已考虑到X射线与物质相互作用的所有可能物理过程。在考虑乳腺摄影设备简化几何结构的同时，还构建了一个压缩乳房的软件体模。该体模可能包含各种成分和尺寸的不均匀性。我们已使用此模型在实际条件下生成蒙特卡罗乳腺造影片。模拟的验证包括物理过程建模和蒙特卡罗乳腺造影片的生成。第一部分通过证明蒙特卡罗数据与理论数据的一致性来完成，而第二部分则通过比较实际乳腺造影片（取自我们构建的简化乳房体模的照射）和在相应曝光条件下对上述体模进行模拟得到的蒙特卡罗乳腺造影片来完成。讨论了该模型的局限性以及蒙特卡罗乳腺造影片的未来用途。
