Tanaka T, Oka Y, Tawara I, Sada T, Kira Y
Department of Cardiology, Showa General Hospital, Kodaira-City, Tokyo, Japan.
Am J Cardiol. 1998 Nov 15;82(10):1275-8, A9. doi: 10.1016/s0002-9149(98)00614-6.
We investigated the acute effects of smoking on coronary flow reserve in terms of the nicotine content of cigarettes in 21 smokers. Coronary flow velocity was measured with a Doppler flow wire. Subjects smoked cigarettes containing >1 mg nicotine (n = 8, group 1) or <1 mg (n = 6, group 2). Subjects in the control group mimicked smoking without a cigarette (n = 7). Coronary flow reserve decreased after smoking in group 1, but not in group 2 or the control group. This reduction may have mediated nicotine or some other unknown substances influenced by smoking.
我们在21名吸烟者中，根据香烟中的尼古丁含量研究了吸烟对冠状动脉血流储备的急性影响。用多普勒血流导线测量冠状动脉血流速度。受试者吸含尼古丁>1毫克的香烟（n = 8，第1组）或<1毫克的香烟（n = 6，第2组）。对照组的受试者模拟吸烟但不使用香烟（n = 7）。第1组吸烟后冠状动脉血流储备降低，但第2组和对照组未降低。这种降低可能是由尼古丁或吸烟影响的其他一些未知物质介导的。
