Stokroos R J, Albers F W, Krikke A P, Casselman J W
Department of Otorhinolaryngology, University Hospital of Maastricht, The Netherlands.
Eur Arch Otorhinolaryngol. 1998;255(9):433-6. doi: 10.1007/s004050050093.
Although gadolinium-enhanced magnetic resonance imaging (Gd-MRI) has been used to indicate the presence of a subclinical labyrinthitis in patients with idiopathic sudden sensorineural hearing loss (ISSHL), its sensitivity in daily clinical practice is unknown. We describe Gd-MRI findings in 27 ISSHL patients taking part in a prospective multicenter clinical trial. MRI findings were related to the severity of the hearing loss, vestibular involvement and the time interval between the occurrence of ISSHL and imaging. Pathological enhancement of the cochlea indicating a labyrinthitis was found in one patient with ISSHL. In 26 cases, no pathological enhancement could be established. Study results indicate that the present sensitivity of Gd-MRI is low for detecting subclinical viral labyrinthitis in patients with ISSHL. To improve the sensitivity of MRI in ISSHL, we recommend that imaging is performed as early as possible, preferably before treatment is started.
尽管钆增强磁共振成像(Gd-MRI)已被用于指示特发性突发性感音神经性听力损失(ISSHL)患者存在亚临床迷路炎,但其在日常临床实践中的敏感性尚不清楚。我们描述了参与一项前瞻性多中心临床试验的27例ISSHL患者的Gd-MRI检查结果。MRI检查结果与听力损失的严重程度、前庭受累情况以及ISSHL发生与成像之间的时间间隔有关。在1例ISSHL患者中发现了提示迷路炎的耳蜗病理性强化。在26例病例中,未发现病理性强化。研究结果表明,目前Gd-MRI检测ISSHL患者亚临床病毒性迷路炎的敏感性较低。为提高MRI在ISSHL中的敏感性,我们建议尽早进行成像检查,最好在开始治疗之前。