Johnson K A, Tung K, Mead G, Sweetenham J
Department of Radiology, Wessex Oncology Centre, Southampton, UK.
Clin Radiol. 1998 Nov;53(11):835-41. doi: 10.1016/s0009-9260(98)80196-7.
We describe the radiological findings at presentation and follow up in 24 adult patients with Burkitt's and Burkitt-like lymphoma, age range 17-67 years. This is an older age group than previously described in North American series, but the clinical and imaging characteristics appear similar. Disease confined to the abdomen was seen in 12 (50%) at presentation, of whom 11 had bowel or mesenteric tumours. Of those with bowel involvement, five patients had disease that had arisen in the ileocaecal region. Intra-abdominal disease was large volume (greater than 5 cm) in the majority of patients. Four patients (17%) had small isolated masses in the head and neck region, two (8%) had isolated unilateral axillary lymphadenopathy. Six (25%) patients presented with disseminated disease, all with hepatic and/or splenic involvement, intra-abdominal and peripheral lymphadenopathy. Three of these patients with disseminated disease were human immunodeficiency virus (HIV) positive. Neurological symptoms were present in a total of five patients at presentation or relapse but positive imaging findings were present in only two patients who had MRI. Computed tomography (CT) head scans performed in four patients were normal. Disease recurrence most commonly occurred within the abdomen.
我们描述了24例年龄在17至67岁之间的伯基特淋巴瘤和伯基特样淋巴瘤成年患者就诊时及随访期间的影像学表现。该年龄组比北美系列报道中描述的年龄更大，但临床和影像学特征似乎相似。就诊时，12例（50%）患者的疾病局限于腹部，其中11例有肠道或肠系膜肿瘤。在肠道受累的患者中，5例患者的疾病起源于回盲部区域。大多数患者的腹腔内疾病体积较大（大于5厘米）。4例（17%）患者在头颈部区域有小的孤立肿块，2例（8%）有孤立的单侧腋窝淋巴结病。6例（25%）患者表现为播散性疾病，均有肝脏和/或脾脏受累、腹腔内和外周淋巴结病。其中3例播散性疾病患者为人类免疫缺陷病毒（HIV）阳性。共有5例患者在就诊或复发时有神经系统症状，但只有2例行MRI检查的患者有阳性影像学表现。4例患者进行的计算机断层扫描（CT）头部扫描结果正常。疾病复发最常见于腹部。
