类固醇激素及绝经后激素替代疗法对女性乳房的生理影响及乳腺癌风险
Physiologic effects of steroid hormones and postmenopausal hormone replacement on the female breast and breast cancer risk.
作者信息
Mustafa I A, Bland K I
机构信息
Department of Surgery, Brown University School of Medicine, and Rhode Island Hospital, Providence 02903, USA.
出版信息
Ann Surg. 1998 Nov;228(5):638-51. doi: 10.1097/00000658-199811000-00003.
Abstract
Most data demonstrate that breast cancer is hormonally influenced. For the woman with no history of breast cancer, the benefits of HRT may outweigh the risks. Although it remains the standard of care to discourage hormone use in patients who have had breast cancer, future studies may result in a change of this standard. There needs to be more research into these complex hormonal interactions so that we will have a better understanding of the true risks and benefits when we attempt to advise our patients regarding the best treatment regimens for them.
摘要
大多数数据表明乳腺癌受激素影响。对于没有乳腺癌病史的女性，激素替代疗法的益处可能超过风险。尽管对于患有乳腺癌的患者，不鼓励使用激素仍然是护理标准，但未来的研究可能会导致这一标准的改变。需要对这些复杂的激素相互作用进行更多研究，以便在我们试图就最佳治疗方案向患者提供建议时，能更好地了解真正的风险和益处。
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