Atta-ur-Rahman Au, Yaqoob M, Farooq A, Anjum S, Asif F, Choudhary MI
International Center for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan.
J Nat Prod. 1998 Nov;61(11):1340-2. doi: 10.1021/np980057n.
Incubation of (1R,2S,5R)-(-)-menthol (1) with Cephalosporium aphidicola for 12 days yielded the six oxidized metabolites: 10-acetoxymenthol (2), 7-hydroxymenthol (3), 4alpha-hydroxymenthol (4), 3alpha-hydroxymenthol (5), 9-hydroxymenthol (6), and 10-hydroxymenthol (7). The structures of the novel compounds 2, 4, 5, and 7 were assigned by interpretation of their spectral data.
将(1R,2S,5R)-(-)-薄荷醇(1)与蚜虫头孢霉一起培养12天，得到了六种氧化代谢产物：10-乙酰氧基薄荷醇(2)、7-羟基薄荷醇(3)、4α-羟基薄荷醇(4)、3α-羟基薄荷醇(5)、9-羟基薄荷醇(6)和10-羟基薄荷醇(7)。通过对新化合物2、4、5和7的光谱数据进行解析确定了它们的结构。
