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非恶性疾病胃切除术后的长期结局

Long-term outcome of completion gastrectomy for nonmalignant disease.

作者信息

Farahmand M, Sheppard B C, Deveney C W, Deveney K E, Crass R A

机构信息

Department of Surgery, Oregon Health Sciences University and Surgical Service, Veterans Affairs Medical Center, Portland, OR 97201, USA.

出版信息

J Gastrointest Surg. 1997 Mar-Apr;1(2):182-7. doi: 10.1016/s1091-255x(97)80107-2.

Abstract

Between 1989 and 1995 we performed completion gastrectomy for non-malignant disease in 21 patients (11 men and 10 women, mean age 48.4 years). These patients had undergone a total of 48 prior gastric operations. Indications for completion gastrectomy in this group were anastomotic ulceration with stricture in eight patients, alkaline reflux gastritis and/or esophagitis in eight, postsurgical gastroparesis in two, gastroesophageal necrosis in two, and gastrocutaneous fistula in one. Major preoperative symptoms included nausea and vomiting in 16 cases, abdominal pain in 15, dysphagia in 14, heartburn in seven, and weight loss in five. Following completion gastrectomy, five patients (24%) had serious complications and there was one postoperative death (5%). Five patients were lost to follow-up. For the remaining 15 patients, mean follow-up has been 30 months with a range of 1 to 70 months. These patients were all interviewed and eight (53%) report significant improvement, two (13%) report moderate improvement, and four (27%) report no improvement; one patient (7%) has had worsening of symptoms since undergoing completion gastrectomy. The average body weight index was essentially unchanged after completion gastrectomy. We conclude that completion gastrectomy with Roux-en-Y esophagojejunostomy results in a favorable outcome in the majority of selected patients with diseases of the foregut who are unresponsive to less radical treatment.

摘要

1989年至1995年间,我们对21例非恶性疾病患者(11例男性,10例女性,平均年龄48.4岁)实施了根治性胃切除术。这些患者此前共接受过48次胃部手术。该组患者根治性胃切除术的指征包括:8例吻合口溃疡伴狭窄、8例碱性反流性胃炎和/或食管炎、2例术后胃轻瘫、2例胃食管坏死、1例胃皮肤瘘。主要术前症状包括:16例恶心呕吐、15例腹痛、14例吞咽困难、7例烧心、5例体重减轻。根治性胃切除术后,5例患者(24%)出现严重并发症,1例术后死亡(5%)。5例患者失访。其余15例患者的平均随访时间为30个月,范围为1至70个月。我们对这些患者均进行了访谈,8例(53%)报告有显著改善,2例(13%)报告有中度改善,4例(27%)报告无改善;1例患者(7%)自接受根治性胃切除术后症状恶化。根治性胃切除术后平均体重指数基本未变。我们得出结论,对于大多数经选择的、对较保守治疗无反应的前肠疾病患者,采用Roux-en-Y食管空肠吻合术的根治性胃切除术可取得良好疗效。

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