Mathias J R, Fernandez A, Sninsky C A, Clench M H, Davis R H
Gastroenterology. 1985 Jan;88(1 Pt 1):101-7. doi: 10.1016/s0016-5085(85)80140-2.
The Roux-en-Y anastomosis is a surgical procedure performed to divert the pancreaticobiliary juices from the gastric pouch in patients who have alkaline reflux gastritis or esophagitis, or both, that develop after vagotomy and Billroth I or II operations. After the Roux-en-Y procedure the inflammation subsides but is often replaced by a characteristic group of symptoms--chronic abdominal pain, nausea, and vomiting worsened by eating. Using a semiconductor recording probe, we investigated the Roux limb in 7 subjects who were fasted and then fed (liquid and solid meals). In the fasted state the migrating motor complex was either completely absent or grossly disrupted. Only 1 subject converted to a fed-state motility pattern in the Roux limb after a liquid meal (Osmolite), and all 7 subjects failed to convert to a fed state after a solid meal. These studies suggest that the Roux-en-Y syndrome of pain, nausea, and vomiting is secondary to a defect in motor function and that the Roux limb is acting as an area of functional obstruction.
Roux-en-Y吻合术是一种外科手术，用于在迷走神经切断术和毕罗I式或II式手术后发生碱性反流性胃炎或食管炎（或两者皆有）的患者中，使胰胆液从胃囊分流。Roux-en-Y手术后，炎症消退，但常被一组特征性症状所取代——慢性腹痛、恶心和进食后加重的呕吐。我们使用半导体记录探头，对7名禁食后再进食（流食和固体食物）的受试者的Roux肠袢进行了研究。在禁食状态下，移行性运动复合波要么完全缺失，要么严重紊乱。只有1名受试者在进食流食（奥米力特）后，Roux肠袢转变为进食状态的运动模式，而所有7名受试者在进食固体食物后均未转变为进食状态。这些研究表明，Roux-en-Y综合征的疼痛、恶心和呕吐是运动功能缺陷的继发表现，且Roux肠袢起到了功能性梗阻区域的作用。
