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将近端胃旁路手术转换为远端胃旁路手术用于治疗超级肥胖患者失败的胃旁路手术。

Conversion of proximal to distal gastric bypass for failed gastric bypass for superobesity.

作者信息

Sugerman H J, Kellum J M, DeMaria E J

机构信息

Division of General and Trauma Surgery, Department of Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298-0519, USA.

出版信息

J Gastrointest Surg. 1997 Nov-Dec;1(6):517-24; discussion 524-6. doi: 10.1016/s1091-255x(97)80067-4.

Abstract

The purpose of this study was to analyze outcome following malabsorptive distal gastric bypass (D-GBP) in superobese patients who were reoperated for recurrent obesity comorbidity after a failed standard gastric bypass (S-GBP). Twenty-seven formerly superobese patients with a failed S-GBP converted to a D-GBP were studied. The small bowel was anastomosed 250 cm from the ileocecal valve to the disconnected Roux limb; the bypassed small intestine was connected to the ileum 50 cm from the ileocecal valve in five patients between 1985 and 1986 and 150 cm from the ileocecal valve in 22 patients thereafter. Comorbidity was reassessed yearly following conversion to D-GBP. Malnutrition occurred in all five patients with a 50 cm "common tract"; all required further revision and two died of hepatic failure. Three of 22 patients with a 150 cm common tract were reoperated with bowel lengthening because of malnutrition. Initial body mass index was 57+/-2 kg/m2 and fell from 46+/-2 kg/m2 before revision to 37+/-2 kg/m2 at 1 year and 32+/-2 kg/m2 at 5 years after revision; the percentage of excess weight lost went from 30+/-4% to 61+/-4% at 1 year and 69+/-5% at 5 years after revision. Preoperative comorbidity in patients undergoing revision included 14 with insulin-dependent type II diabetes mellitus, 11 with sleep apnea, 14 with hypoventilation, 13 with hypertension, and two with venous stasis ulcers. Obesity comorbidity was corrected within 1 year in all but two patients with hypertension and remained stable in all patients followed for 5 years. Revision of a failed S-GBP to a 150 cm common tract D-GBP corrects failed weight loss and severe obesity comorbidity but requires nutritional support to prevent protein-calorie malnutrition, iron and fat-soluble vitamin deficiencies, and further revision in some patients to correct malnutrition. A 50 cm common tract has an unacceptable morbidity and mortality.

摘要

本研究的目的是分析超级肥胖患者在标准胃旁路术(S-GBP)失败后因复发性肥胖合并症接受再次手术的吸收不良性远端胃旁路术(D-GBP)后的结局。对27例曾接受S-GBP但失败后转而接受D-GBP的超级肥胖患者进行了研究。小肠在距回盲瓣250 cm处与离断的Roux袢吻合;1985年至1986年间,5例患者的旷置小肠在距回盲瓣50 cm处与回肠相连,此后22例患者的旷置小肠在距回盲瓣150 cm处与回肠相连。转为D-GBP后每年重新评估合并症情况。5例“共同通道”为50 cm的患者均发生了营养不良;所有患者均需进一步修正手术,2例死于肝功能衰竭。22例“共同通道”为150 cm的患者中有3例因营养不良接受了肠道延长再次手术。初始体重指数为57±2 kg/m²,修正术前为46±2 kg/m²,修正术后1年降至37±2 kg/m²,5年降至32±2 kg/m²;超重减轻百分比从修正术前的30±4%增至术后1年的61±4%,5年时为69±5%。接受修正手术患者的术前合并症包括14例胰岛素依赖型II型糖尿病、11例睡眠呼吸暂停、14例通气不足、13例高血压和2例静脉淤滞性溃疡。除2例高血压患者外,所有患者的肥胖合并症在1年内得到纠正,所有随访5年的患者病情保持稳定。将失败的S-GBP修正为“共同通道”为150 cm的D-GBP可纠正减肥失败和严重肥胖合并症,但需要营养支持以预防蛋白质-热量营养不良、铁和脂溶性维生素缺乏,并在部分患者中进行进一步修正手术以纠正营养不良。“共同通道”为50 cm的手术具有不可接受的发病率和死亡率。

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