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[心房扑动的消融。8年经验后的长期结果]

[The ablation of atrial flutter. The long-term results after 8 years of experience].

作者信息

García-Cosío F, López Gil M, Arribas F, Goicolea A, Pastor A, Núñez A

机构信息

Servicio de Cardiología, Hospital Universitario de Getafe, Madrid.

出版信息

Rev Esp Cardiol. 1998 Oct;51(10):832-9. doi: 10.1016/s0300-8932(98)74827-4.

Abstract

OBJECTIVE

Since the 1990's radiofrequency ablation radiofrequency ablation of atrial flutter has evolved in its methods and results. We have reviewed the long term outcome in 62 patients with typical (common) or reversed (clockwise) flutter undergoing radiofrequency ablation between 1990 and 1997.

PATIENTS AND METHODS

Fifty men and 12 women, aged 22-78 years (57 +/- 12) with flutter recurring after cardioversion and antiarrhythmic drugs make this series. Flutter was typical in 59 cases and reversed in 3. There was no heart disease in 14, bronchopulmonary disease in 10, coronary disease in 9, cardiomyopathies in 6 and other processes in the remainder. In 5 cases with previous surgery for atrial or ventricular septal defect, Ebstein's anomaly or myxoma, we treated also a macro-reentry tachycardia around the atriotomy in the right atrium. Radiofrequency ablation was directed to the inferior vena cava-tricuspid isthmus in typical and reversed flutter, and to the isthmus between the inferior end of the atriotomy and the inferior vena cava, in the lateral right atrium, in the atriotomy tachycardias. We subdivided our patients in Group 1 (24 patients), treated until the end of 1994, and Group 2 (38 patients) treated since 1995 using specially designed catheters and trying to produce isthmus block as the endpoint of the procedure.

RESULTS

Radiofrequency ablation interrupted flutter in 61 of 62 cases (98.4%), and the atriotomy tachycardia in all 5. The number of application in Group 1 was 18.6 +/- 10.1 vs 12 +/- 10 in Group 2 (p < 0.05). Follow-up was 40 +/- 24 months in Group 1 vs 16 +/- 9.5 in Group 2. Flutter recurred in 58% of Group 1 and 13% of Group 2 patients (p < 0.001), usually 1-3 months after radiofrequency ablation and they were successfully treated by new radiofrequency ablation with a small number of applications. There was no recurrence of atriotomy tachycardia. Atrial fibrillation occurred in 14 patients (23%) (11 paroxysmal, 3 persistent), with equal incidence in both groups. At the end of follow-up 85% of the patients were in sinus rhythm, although 6 needed pacemakers for sinus node dysfunction (3) or AV ablation (3). Antiarrhythmic drugs were used by 46% of patients in Group 1 and 26% in Group 2 (p = NS) for atrial arrhythmias or recurrent flutter.

CONCLUSIONS

Radiofrequency ablation is an effective treatment for flutter and macro-reentry atriotomy tachycardia. Progress in methods have improved results significantly. Atrial fibrillation can still be a problem in 20-25% of the patients after flutter control.

摘要

目的

自20世纪90年代以来,心房扑动的射频消融在方法和结果方面不断发展。我们回顾了1990年至1997年间62例典型(常见)或逆向(顺时针)扑动患者接受射频消融的长期结果。

患者与方法

本系列包括50名男性和12名女性,年龄在22 - 78岁(57±12岁),这些患者在心脏复律和抗心律失常药物治疗后仍有扑动复发。其中59例为典型扑动,3例为逆向扑动。14例无心脏病,10例有支气管肺部疾病,9例有冠心病,6例有心肌病,其余患者有其他病症。5例曾接受房间隔或室间隔缺损、埃布斯坦畸形或黏液瘤手术,我们还治疗了右心房手术切口周围的大折返性心动过速。对于典型和逆向扑动,射频消融针对下腔静脉 - 三尖瓣峡部;对于手术切口性心动过速,射频消融针对右心房外侧手术切口下端与下腔静脉之间的峡部。我们将患者分为两组,第1组(24例患者),治疗至1994年底;第2组(38例患者),自1995年起使用专门设计的导管进行治疗,并试图将峡部阻滞作为手术终点。

结果

62例患者中有61例(98.4%)的扑动被射频消融打断,5例手术切口性心动过速均被打断。第1组的消融次数为18.6±10.1次,第2组为12±10次(p<0.05)。第1组的随访时间为40±24个月,第2组为16±9.5个月。第1组58%的患者扑动复发,第2组为13%(p<0.001),通常在射频消融后1 - 3个月复发,再次进行少量应用的射频消融后成功治愈。手术切口性心动过速无复发。14例患者(23%)发生心房颤动(11例阵发性,3例持续性),两组发生率相同。随访结束时,85%的患者处于窦性心律,尽管有6例因窦房结功能障碍(3例)或房室结消融(3例)需要起搏器。第1组46%的患者和第2组26%的患者(p=无显著差异)因房性心律失常或复发性扑动使用抗心律失常药物。

结论

射频消融是治疗扑动和大折返性手术切口性心动过速的有效方法。方法的进步显著改善了治疗效果。在控制扑动后,20% - 25%的患者仍可能出现心房颤动问题。

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