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[心房扑动和心房颤动的射频导管消融术]

[Radiofrequency catheter ablation of atrial flutter and atrial fibrillation].

作者信息

Reithmann C, Hoffmann E, Steinbeck G

机构信息

Medizinische Klinik I, Klinikum Grosshadern, Universität München.

出版信息

Herz. 1998 Jun;23(4):209-18. doi: 10.1007/BF03044317.

Abstract

Radiofrequency catheter ablation is now considered as a curative approach in patients with typical atrial flutter. Typical atrial flutter is due to a macrore-entrant circuit within the right atrium and it can be eliminated by a linear lesion in the isthmus between the tricuspid annulus and the vena cava inferior. The electrophysiological criterion of a bidirectional isthmus block has been shown to reduce the recurrence rate of atrial flutter after catheter ablation, thus achieving long-term cure of typical atrial flutter. Acute success rates of 85 to 90% and recurrence rates of 10 to 15% have been reported. The risk of paroxysmal atrial fibrillation continues to be clinically relevant in patients who underwent successful ablation of atrial flutter, in particular in patients with previously documented atrial fibrillation. The incidence of a new onset of atrial fibrillation after ablation of atrial flutter seems to be approximately 20%. Isthmus ablation has also been shown to be beneficial for the majority of patients with typical atrial flutter and atrial fibrillation: In addition to an elimination of typical atrial flutter the isthmus ablation apparently reduces the incidence of paroxysmal atrial fibrillation. At present, atrial fibrillation can only be treated by catheter ablation as a curative approach in the rare cases where an accessory pathway, an AV nodal re-entrant tachycardia, typical atrial flutter or an ectopic atrial tachycardia is the induction mechanism of the atrial fibrillation. The majority of patients with atrial fibrillation is apparently not amenable to a curative local ablation. While AV junction ablation and AV node modification can palliate some of the symptoms of atrial fibrillation by a control of ventricular rate, the arrhythmia persists with the loss of AV synchrony and continued risk of thromboembolism. The surgical MAZE procedure implies a compartimentation of the atria by surgical incisions resulting in areas to small to sustain the arrhythmia. Based on this procedure experimental and clinical studies are currently performed in order to develop catheter ablation cure of atrial fibrillation.

摘要

射频导管消融术目前被认为是治疗典型心房扑动患者的一种根治性方法。典型心房扑动是由右心房内的大折返环引起的,通过在三尖瓣环和下腔静脉之间的峡部进行线性消融可以消除。双向峡部阻滞的电生理标准已被证明可降低导管消融术后心房扑动的复发率,从而实现典型心房扑动的长期治愈。据报道,急性成功率为85%至90%,复发率为10%至15%。在成功消融心房扑动的患者中,阵发性心房颤动的风险在临床上仍然相关,特别是在既往有记录的心房颤动患者中。心房扑动消融术后新发心房颤动的发生率似乎约为20%。峡部消融对大多数典型心房扑动和心房颤动患者也有益:除了消除典型心房扑动外,峡部消融显然还降低了阵发性心房颤动的发生率。目前,在极少数情况下,当附加旁路、房室结折返性心动过速、典型心房扑动或异位房性心动过速是心房颤动的诱发机制时,心房颤动只能通过导管消融作为一种根治性方法进行治疗。大多数心房颤动患者显然不适合进行根治性局部消融。虽然房室结消融和房室结改良可以通过控制心室率缓解心房颤动的一些症状,但心律失常仍会持续,同时会失去房室同步并持续存在血栓栓塞风险。外科迷宫手术意味着通过手术切口将心房分隔成小区域,从而无法维持心律失常。基于此手术,目前正在进行实验和临床研究,以开发导管消融治愈心房颤动的方法。

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