Marty J, Samain E
Service d'anesthésie-réanimation, hôpital Beaujon, université Paris VII, Clichy.
Arch Mal Coeur Vaiss. 1998 Aug;91 Spec No 4:23-8; discussion 29-30.
General anesthesia changes circulatory haemodynamics in three ways: a decrease in sympathetic tone, a decrease in VO2, and a change in baroreceptor reflex function. These effects may have important consequences in patients with cardiovascular disease whose stability depends on these different factors. In addition, the anaesthesia should be adapted to the intensity of the surgical stimuli which tend to increase sympathetic activity, produce tachycardia and increase the blood pressure which may cause decompensation of some cardiac diseases (coronary artery disease for example). Drugs used in the treatment of cardiac disease may interfere with anaesthesia but they are usually continued in order to operate patients under stable cardiovascular conditions.
交感神经张力降低、氧耗量降低以及压力感受器反射功能改变。这些效应对于心血管疾病患者可能具有重要影响，因为他们的病情稳定取决于这些不同因素。此外，麻醉应根据手术刺激的强度进行调整，手术刺激往往会增加交感神经活动、导致心动过速并升高血压，这可能会使某些心脏病（例如冠状动脉疾病）失代偿。用于治疗心脏病的药物可能会干扰麻醉，但通常会继续使用这些药物，以便在稳定的心血管状况下为患者进行手术。
