[智障人士职业中心的甲型、乙型和丙型肝炎]

[Hepatitis A, B, and C in an occupational center for the mentally handicapped].

作者信息

Arnedo A, Latorre M D, Pac M R, Safont L, Guillén F, Aguinaga I

机构信息

Sección de Epidemiología, Centro de Salud Pública, Castellón.

出版信息

Enferm Infecc Microbiol Clin. 1998 Oct;16(8):370-3.

PMID:9835153

Abstract

BACKGROUND

Estimation of prevalence of serologic markers of viral hepatitis A, B and C in students and staff of an occupational centre in Castellón (Spain).

METHODS

Serologic markers of hepatitis A (IgG anti-HAV) and B (HBsAg, anti-HBe, anti-HBc, anti-HBs) were detected by radioimmunoassay (RIA) and serologic markers of hepatitis C (anti-HCV) by immunoradiometric assay (IRMA). Ninety per cent of students (54/60) and 80% of staff (8/10) participated.

RESULTS

The prevalence of IgG anti-HVA was 55.6% in students and 75% in staff, increasing with age. Considering persons not vaccinated against hepatitis B, the prevalence of serologic markers hepatitis B was 18.5% in students, two HBsAg and anti-HBe positive, and nobody in staff. Serologic markers hepatitis B was associated with duration of stay institutions for mentally handicapped. None of the center was positive for anti-HCV.

CONCLUSIONS

Viral hepatitis prevalences present notable differences. To maintain a serological surveillance of these diseases is important to control and prevention.

摘要

背景

对西班牙卡斯特利翁一个职业中心的学生和工作人员进行甲型、乙型和丙型病毒性肝炎血清学标志物患病率的评估。

方法

采用放射免疫分析法（RIA）检测甲型肝炎（抗-HAV IgG）和乙型肝炎（HBsAg、抗-HBe、抗-HBc、抗-HBs）的血清学标志物，采用免疫放射分析测定法（IRMA）检测丙型肝炎（抗-HCV）的血清学标志物。90%的学生（54/60）和80%的工作人员（8/10）参与了检测。

结果

抗-HVA IgG的患病率在学生中为55.6%，在工作人员中为75%，且随年龄增长而升高。对于未接种乙型肝炎疫苗的人群，学生中乙型肝炎血清学标志物的患病率为18.5%，有两人HBsAg和抗-HBe呈阳性，工作人员中无人阳性。乙型肝炎血清学标志物与智障人士在机构中的停留时间有关。该中心无人抗-HCV呈阳性。