Bursian A V, Sviderskaia G E
Zh Evol Biokhim Fiziol. 1976 Jul-Aug;12(4):322-7.
Reactions of the spinal motor center to tetanic stimulation of afferent nerve fibers in the peripheral nerve or dorsal roots L4--L6, have been investigated in rat pups ageing from 1 to 30 days. EMG was recorded in m. gastrocnemius. Within the first 12 days, in response to a constant stimulation periodic motor activity was observed which in its pattern was similar to the spontaneous cycles in newborn animals. On further development of rats, periodic form of the reaction is abolished, although it may be elicited after decerebration or during fatigue caused by a prolondged tetanization. Within the first week, tetanization of the afferents by the increasing stimuli either does not affect the periodic pattern of the activity, or results in a stepwise increase of the amplitude and duration of separate periods. On further development, gradual dependence of the intensity of the response from the stimulus strength is established, which is associated with functional differentiation of various motor units. The data obtained are discussed in relation to the role of afferent systems in evolution of functions of the central nervous system.
对1至30日龄幼鼠脊髓运动中枢对外周神经或L4-L6背根传入神经纤维强直刺激的反应进行了研究。在腓肠肌记录肌电图。在出生后的前12天内，对持续刺激会观察到周期性运动活动，其模式类似于新生动物的自发周期。在大鼠进一步发育过程中，反应的周期性形式消失，尽管在大脑去皮质后或长时间强直刺激引起的疲劳期间可能会引发这种周期性。在第一周内，增加刺激对传入神经进行强直刺激，要么不影响活动的周期性模式，要么导致各个周期的幅度和持续时间逐步增加。在进一步发育过程中，建立了反应强度对刺激强度的逐渐依赖性，这与各种运动单位的功能分化有关。结合传入系统在中枢神经系统功能进化中的作用对所得数据进行了讨论。
